A previous study has reported that in the microenvironment of human neuroblastoma, GAL‐3BP interacts with GAL‐3 in bone marrow mesenchymal stem cells and induces transcriptional upregulation of IL‐6, via the Gal‐3BP/Gal‐3/Ras/MEK/ERK signaling pathway [45, 46]. The gene discussed is LGALS3; the disease is neuroblastoma.