When the analysis was repeated using just the 2 PREDICT categories, the crude breast cancer mortality rates were 1.00 and 2.54 for Ki67 scores of 0%-10% and 11%-100%, respectively (Ptrend < .001, Figure 2, C, top panel), leading to 8-year cumulative breast cancer mortality risks of 2.4% (95% CI = 2.1% to 2.8%) and 6.0% (95% CI = 5.3% to 6.9%), respectively (Figure 3, C, top panel). Here, MKI67 is linked to breast cancer.