When the above analyses were repeated based solely on the 3 categories specified in the IKWG consensus, the crude breast cancer mortality rate ratios were 1.00, 1.42, and 5.56 for Ki67 scores of 0%-5%, 6%-29%, and 30%-100%, respectively (Ptrend < .001, Figure 2, B, top panel). The gene discussed is MKI67; the disease is breast cancer.