In comparison to PAMs infected with ASFV-WT, the differentially expressed mRNAs during Del2R infection were mainly involved in innate immunity signaling pathways such as NF-κB, TNF, MAPK, and PI3K-AKT signaling pathways, as well as receptor signaling, metabolic networks, and other pathways associated with viral infection (Fig 2B). This evidence concerns the gene TNF and viral infectious disease.