C3 and polycystic ovary syndrome: The functional fragment of C3 cleavage, C3b, was not different in obese PCOS or nonobese PCOS women compared to their controls (Table 2); however, its cleavage product iC3b was significantly elevated in both nonobese PCOS (p = 0.02) and obese PCOS (p < 0.001) compared to controls.