BMI correlated positively in both obese and nonobese PCOS with factor B (r = 0.36, p < 0.0001 obese PCOS: r = 0.66, p < 0.0001 nonobese PCOS), factor H (r = 0.51, p < 0.0001 obese PCOS: r = 0.58, p < 0.0001 nonobese PCOS) and C5a (r = 0.44, p < 0.0001 obese PCOS: r = 0.61, p < 0.0004 nonobese PCOS). This evidence concerns the gene PPIB and polycystic ovary syndrome.