Our data imply that apoptotic ATRA-APL cells-derived CD14(+)apo-MP promote the recipient viable ATRA-APL cells in the efferocytic engulfment of apoptotic cells, and this prevents the release of pro-inflammatory cytokines from apoptotic cells and the recruitment of ATRA-APL cells into alveolar space during the resolution phase of DS in APL patients. The gene discussed is CD14; the disease is acute promyelocytic leukemia.