CCNB1 and Hepatic fibrosis: Subsequently, the expression of Anln, Hmmr, Tpx2, Ccnb1, and Ccnb2 was measured in activated hepatic stellate cells (HSCs), which have been shown to become myofibroblast-like cells known to contribute to the progression of liver fibrosis through the deposition of extracellular matrix proteins [54].