TBK1 and amyotrophic lateral sclerosis: Several genes have been identified which could impact both FTD and ALS, including chromosome 9 open reading frame 72 (c9orf72), TAR DNA Binding Protein (TARDBP), Sequestosome 1 (SQSTM1), Valosin Containing Protein (VCP), Fused In Sarcoma (FUS), TANK Binding Kinase 1 (TBK1), or Cyclin F (CCNF) [9].