MMP2 and glioblastoma: Pan-cancer analysis showed that MM9 was almost always downregulated among the 16 tumors, including GC; MMP2 was upregulated in BLCA, CESC, KICH, and UCEC and downregulated in CHOL, GBM, HNSC, KIRP, PRAD, SKCM, and GC (Fig. 7A and B).