Whole-exome, whole-genome, and single-cell RNA sequencing were implemented in the mentioned study on matched adjoining normal tissues, multiregional exemplified adenomas at various levels, and carcinomas from 6 FAP and 1 MUTYH-associated polyposis patients.41 In a recent study carried out through whole-exome sequencing, a point variant in the noncoding region in the APC gene was determined.42 Another recent study examined the findings of APC gene analyses. The gene discussed is APC; the disease is Familial adenomatous polyposis.