Among these proteins, creatine kinase‐MB (CK‐MB), an isoenzyme commonly used for the clinical diagnosis of acute myocardial infarction (Ghormade et al., 2014) was also found to be upregulated in the plasma of children with HGPS compared to controls, although the levels fell within the normal range of the assay (Gordon, Campbell, et al., 2018). The gene discussed is ZMPSTE24; the disease is acute myocardial infarction.