IGF1 and Hutchinson-Gilford progeria syndrome: Despite the fact that IGF‐1 is not usually downregulated in patients with HGPS (Merideth et al., 2008), which highlights the inherent differences between humans and preclinical models, the exploration of this gene set and related pathways may lead to new clues to unveil the molecular mechanisms underlying the reduced growth and poor weight gain associated with HGPS.