In the NE(PD1nb) group, the polarized type of tumor‐infiltrating DCs was changed after administration, such as CD11b+ DCs (cDC2s), and CD8+ DCs (resident cDC1s),[51, 52] and their levels significantly increased compared with those in the PBS group, which suggests that DCs were activated and regulated the tumor‐related immune response after treatment with NE(PD1nb) (Figure S18A,B, Supporting Information). This evidence concerns the gene ITGAM and neoplasm.