NFKB1 and cervical carcinoma: According to a different study, Fisetin inhibits the migration and invasion of the human cervical cancer cells SiHa and CaSki, which provide significant support for the hypothesis that fisetin inhibits aggressive behaviors by downregulating the expression of the uPA gene by inhibiting the p38 MAPK-dependent NF-κB signaling pathway.43A novel combination technique using fisetin and sorafenib on human cervical cancer cell lines demonstrated a potent anticancer impact both in-vitro and in-vivo.