This inhibits the migration and invasion of cne1-lmp1 cells.32While the nuclear translocation of YB-1 can be blocked by fisetin directly, EMT-induced expression of Y box-1 (YB-1) can accelerate the EMT in PCa.33As shown by kinetic studies and computational docking, Fisetin binds to the cold shock domain. Here, YBX1 is linked to posterior cortical atrophy.