PTGS2 and colorectal cancer: The results showed (Figure 11) that vitexin significantly enhanced the inhibition of NF-κB expression in colorectal cancer HT-29 cells by 2.5 mM aspirin, suggesting the enhanced inhibition of COX-2 expression in colorectal cancer HT-29 cells by vitexin may be achieved by inhibiting the activity of NF-κB.