The box diagram shows that the expression levels of IL6, NFKBIA, CSF1, CXCL1, IL1R1, SOCS3, and CASP1 in symptomatic COVID-19 cases with myocardial injury were significantly higher than those in uninfected healthy individuals and asymptomatic COVID-19 cases, whereas MYC and TNFRSF1A were lower than those in uninfected healthy individuals and asymptomatic COVID-19 cases (P<0.05) (Figures 6A, B). The gene discussed is IL1R1; the disease is COVID-19.