To examine the degree of tumour heterogeneity, the coefficient of determination (R2 value) of the global transcriptome (CPM of ∼22,000 genes/sample) was calculated between samples from each group (WT and Inha KO ‘N’, ‘TAT’ and ‘TM’, including single tumours from multiple animals (multiple animals), tumours from both testes from the same animal (single animal, both testes), and tumours within a single testis (single animal, single testis) (Figure 4E). This evidence concerns the gene INHA and neoplasm.