Among autophagy genes in the Reactome database, PRMT1 was negatively correlated with genes such as ATG9A, DYNC1H1, EPAS1, PINK1, TSC1, TUBB6, and ULK1 in gastric tumor tissues (STAD-TCGA) (Fig. 6J and S6E) and positively correlated with HMMR, ESCO2, CHAC2, and NUDT6 (STAD-TCGA) (Fig. 6K and S6F). The gene discussed is CHAC2; the disease is gastric neoplasm.