HNRNPL and PTBP1 can also be competitively bound by the lncRNA SNHG6, thereby restraining its stabilizing effect on SETD7 and LZTFL1, causing rapid degradation of SETD7 and LZTFL1 mRNAs and eventually promoting HCC progression30. The gene discussed is LZTFL1; the disease is hepatocellular carcinoma.