FANCE and Friedreich ataxia: Fanconi anemia complementation group E (FANCE) plays a core role in the FA pathway and is involved in the construction of FA core complexes (FANCA, -B, -C, -E, -F, -G, -L, -M, -T) and linking downstream FANCD2-FANCI monoubiquitylation complexes, DNA damage repair proteins (FANCD1, -J, -N, -O, -P, -Q, -R, -S, -U, -V, -W) and their coordinated FA-associated proteins [7, 8].