The pan-cancer analysis performed by a TNMPlot online tool (https://tnmplot.com/analysis/) of the available normal (non-cancerous) and tumor RNA-Seq data shows that the level of F11R gene product was significantly altered (increased or decreased) in virtually all cancer types, excluding renal papillary cell carcinoma, liver, stomach and thyroid cancer (Fig. 1A). The gene discussed is F11R; the disease is papillary renal cell carcinoma.