CHEK2 and triple-negative breast carcinoma: In fact, for all 9 genes, the results between the two studies are completely consistent for the molecular subtypes with the highest mutation frequency per gene: PVs in BARD1, BRCA1, RAD51C and RAD51D were most common in triple-negative breast cancer, ATM, BRCA2 and PALB2 were enriched in the Luminal B-like subtype (ER + , HER2-, NHG 3), CHEK2 was most frequently mutated in the ER + , HER2 + subtype, and TP53 was enriched in HER2 + subtypes.