Additionally, in ovarian cancer cells, where mutp53 or ENTPD5 depletion did not affect ITGA5 and ITGB1 expression levels (Supplemental Fig. 1), we observed no inhibition of FN binding by mutp53 or ENTPD5 depletion (Supplemental Fig. 3). The gene discussed is ITGB1; the disease is ovarian carcinoma.