In the ovarian carcinoma cells, where ITGA5 and ITGB1 were expressed independently of mutp53 and ENTPD5, adhesion to FN was only reduced by direct depletion of ITGA5 and ITGB1, but not affected by siRNAs targeting mutp53 and ENTPD5 (Supplemental Fig. S3c-d). The gene discussed is ITGA5; the disease is ovarian carcinoma.