SPOCK3 and Familial prostate cancer: This study is committed to investigate the effect of SPOCK3 on the malignant progression of prostate cancer and construct a prognostic model for disease-free survival (DFS) in patients with prostate cancer by demonstrating SPOCK3 as a risk factor for OS in prostate cancer patients, which is associated with prostate cancer immune cell infiltration and its important role in the development of prostate cancer.