LDB3 and left ventricular noncompaction: Failure of this process to occur leads to left ventricular noncompaction with numerous trabeculations and deep recesses between them [2] Various genetic defects have been associated with LVNC, including mutations in the Z-band alternatively spliced PDZ-motif protein (ZASP) gene on chromosome 10 [10, 13] These mutations could be sporadic or familial.