For instance, in a female patient affected with autism and ID with t(14;21)(q21.1;p11.2)dn and 2.6 Mb of microdeletion comprising 15 genes at 2q31.1, the causative gene LRFN5 (Leucine-Rich Repeat and Fibronectin Type III Domain-Containing Protein 5, MIM 612811) was found dysregulated at the 14q21.1 translocation breakpoint31. The gene discussed is LRFN5; the disease is autism.