Flow cytometry (FC) analysis and quantification of GFP+ cells confirmed that productive infection in cells lacking VAP-A and ORP3 is low, i.e., 4.56 ± 2.03% and 2.01 ± 0.09%, respectively, in contrast to >35% in scrambled shRNA or VAP-B-deficient cells (Fig. 3f, g), supporting the idea that the integrity of the VOR complex is necessary for this process. Here, VAPA is linked to infection.