It has been shown that both mitoferrin-deficient zebrafish and alas2-deficient zebrafish exhibit anaemia, and the haemoglobin production defect in mitoferrin-deficient zebrafish, but not alas2-deficient zebrafish, is restored by the treatment with hinokitiol (1 μM) and ferric citrate (10 μM)14. The gene discussed is ALAS2; the disease is anemia.