We then compared transition points in CA27 metastases and the prostate tumors harvested at death split by whether the AR inversion break-point was detected (Fig. 3c): although all tumors shared the majority of transition points, the two break-point negative prostate tumors had a high proportion of transition points that were not shared with any metastases in contrast to the break-point positive prostate tumor (and all other metastases) (Fig. 4c). The gene discussed is AR; the disease is prostate neoplasm.