CAR[D]-T, CAR[E]-T and to some extent CAR[C]-T also showed potent cytotoxicity against glioblastoma cell lines expressing lower levels of IL13Rα2 (Fig. 1f; Fig. S2b–e) and secreted IFN-γ in a dose-dependent manner (Fig. 1g, h; Fig. S2f–g) and IL-2 (Fig. S2h–i). Here, IL2 is linked to glioblastoma.