Another study, using a different induction protocol, found spontaneous aortic aneurysms in the Myh11-CreERT2–YAP/TAZ-KO model and attributed this to cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS)/stimulator of interferon genes (STING) activation (5). This evidence concerns the gene STING1 and aortic aneurysm.