In addition to a reduction in the weight of all fat depots (epididymal WAT [eWAT], iWAT, retroperitoneal WAT [rpWAT], and iBAT), liver weight and hepatic steatosis were also reduced in Snap25Δ3/Δ3 mice compared with Snap25+/+mice (Figure 4, D and E). The gene discussed is SNAP25; the disease is fatty liver disease.