BSG and infection: CD147 is a membrane glycoprotein known to be involved in infection by eukaryotic, prokaryotic and viral pathogens (Fenizia et al., 2021), and may also bind to SARS-2S and mediate the cell entry of SARS-CoV-2 through endocytosis (Brodowski et al., 2022; Cavezzi et al., 2022; Kalejaiye et al., 2022), although infection mediated by CD147 is most likely secondary because CD147 is highly expressed in neural tissues but not in respiratory tract (Qiao et al., 2020).