According to the results of examination, the tumor produces hormones (hypercorticism): cortisol – 375.7 nmol/l, ACTH – 4.1 pmol/l (6 – 58), aldosterone – 130.7 pg/ml (<199), and renin – 3.9 ulU/ml (2.79 – 61.83). The gene discussed is REN; the disease is neoplasm.