VE staining of ALDH has been reported only in tissues of kidney cancer (specifically renal cell carcinoma, a well-known angiogenic tumor) where double immunofluorescence staining of the frozen sections of human renal tumors and normal kidney tissues was performed using anti-ALDH antibody, and the ALDH staining was proven to be negative in normal blood vessels, but was strongly positive in tumor blood vessels [6]. This evidence concerns the gene LDHA and hereditary clear cell renal cell carcinoma.