For instance, mouse-derived mmu-miR-92a-2-5 can target TLR2 to inhibit Schistosoma japonicum-induced liver fibrosis and downregulate the expression of TLR2-related cytokines such as IL-4, IFN-γ, and TNF-α during S. japonicum infection in mice (41). Here, IL4 is linked to Hepatic fibrosis.