Among them, 36 have familial Mediterranean fever (53.7% of all autoinflammatory diseases) [7, 62, 65, 70, 75, 115, 128], 4 have Blau syndrome (6%) [62, 125], 3 have Aicardi-Goutières syndrome (4.5%) [97, 103, 118], 3 have familial cold autoinflammatory syndromes 1 (4.5%) [65, 128], 2 have ADA2 deficiency (3%) [73, 125], 2 have NLRP1 deficiency (3%) [19, 62], 2 have TNF receptor-associated periodic syndrome (%) [81, 125], 2 have hyperpigmentation hypertrichosis, histiocytosis-lymphadenopathy plus syndrome SLC29A3 mutation (3%) [119, 125], and 2 have RNASEH2B deficiency (3%) [95]. The gene discussed is ADA2; the disease is familial cold autoinflammatory syndrome.