According to computational identification of SARS-CoV-2-encoded miRNAs, we can mention binding of miR385-3p to 5′-UTR TGFBR3 as a major immunosuppressant, binding of MR147-5p to two inflammatory proteins such as CXCL16 and ARRB2, binding of MR66-3p to tumor necrosis factor (TNF)-activator, binding of miR147-3p to TMPRSS2 enhancer, binding of miR198-3p to interferon (IFN)-related genes, and finally binding of miR359-5p and miR328-5p to proteins associated with viral infection such as MYH9 and RARA [31]. The gene discussed is TNF; the disease is viral infectious disease.