SOCS1 and ulcerative colitis: MiRNA-31-5p is also elevated in inflamed ulcerative colitis mucosa, where it suppresses the expression of signal transducer and activator of transcription 6 (STAT6), suppressor of cytokine signaling 1 (SOCS1), and eotaxin-3 (CCL26) via downregulating the IL-13 receptor α-1 (IL13Rα-1) gene [76].