We then examined eight genesets representative of processes key to the cancer-immunity cycle, including co-stimulation and inhibition of antigen presenting cells (APCs), tumor antigen cross-presenting BATF3 dendritic cell (DC) expression, co-stimulation and inhibition of T cells, major histocompatibility class I (MHC I) molecule expression, interferon gamma signaling, and cytolytic activity7,31,32 (Fig. 2b). The gene discussed is IFNG; the disease is cancer.