Compared to c-Scorelo+med, c-Scorehi tumors had increased transcriptional patterns associated with the presence of M1-type macrophages, CD8+ T cells, and T Regulatory cells in most tumor types (Supplementary Fig. 1b; enriched in 96%, 88%, 64% of tumor types, respectively, Wilcoxon rank-sum, FDR adjusted). The gene discussed is CD8A; the disease is neoplasm.