AMOTL1 and nasopharyngeal carcinoma: Furthermore, AMOTL1-L was upregulated in NPC samples compared with control samples (Fig. 4C), and the ratio of AMOTL1-L/S was positively correlated with the expression of SRSF3 in the NPC samples (P = 0.034, Fig. 4D) and NPC cell lines (Fig. 4E, Supplementary File 1) compared with their corresponding controls, suggesting the regulation of SRSF3 on AMOTL1 splicing.