C4B and Alzheimer disease: We identified 11 DEGs by intersecting the 15 previously identified DEGs from HFD cohort with DEGs from AD cohort and they were Dnajb14, Gas7, Lgi2, C4b, Gdpd2, Ddr1, Col16a1, Sbno2, Adam8, Kcnj2, Csf2ra (Fig. 3C).