The results showed that age (hazard ratio (HR), 1.046; 95%CI, 1.032-1.061; p < 0.0001), lactate dehydrogenase (LDH) (HR, 1.002; 95% CI, 1.001-1.003; p = 0.003), albumin (ALB) (HR, 0.746; 95% CI, 0.642-0.866; p < 0.0001), ISS stage (HR, 1.355; 95% CI, 1.113-1.650; p = 0.002), and PRMT1 expression (HR, 1.966; 95% CI, 1.400-2.759; p < 0.0001) were independent prognostic factors for survival of MM patients (Supplementary Table 3). The gene discussed is PRMT1; the disease is Miyoshi myopathy.