A recent study also demonstrated that these periodontal bacteria can also promote CRC development increasing the expression of a specific microRNA (miR‐218‐5p) in cells and exosomes, inhibiting the expression of PTPRR and enhancing the RAS/ERK/C‐FOS signaling pathway, which leads to colon cells overgrowth [105]. The gene discussed is FOS; the disease is colorectal carcinoma.