To elucidate whether these affect SSB1 condensation, we generated two constructs SSB1(S172P/H173L) (Ser172 to proline and His173 to leucine) and SSB1(R206Q) (Arg206 to glutamine) based on cancer-derived mutations (Fig. 5a and Extended Data Fig. 8k). The gene discussed is NABP2; the disease is cancer.