GPT and Decreased total leukocyte count: The most common treatment-related grade 3/4 AEs and laboratory abnormalities regardless of relationship were hematological disorders including anemia (27.4%), leukopenia (32.9%) and neutropenia (43.8%; grade 4, 19.2%; febrile neutropenia, 4.1%); fatigue (4.1%), nausea (2.7%), diarrhea (2.7%), and increased liver function tests, including increased transaminases (ALT, 4.2%; AST, 1.4%), alkaline phosphatase (5.6%) and GGT (19.2%).