CCL24 and colonic neoplasm: Further to the inflammatory and profibrotic activity promoted by CCL24, it was also shown to be involved in angiogenesis-related pathways.68 Several studies have demonstrated that CCL24 may affect endothelial cell tube formation, migration, and invasion features.54 These effects are driven by specific mediators including toll-like receptor 4 and VEGF-A.54,69 Also, CCL24 signaling was shown to play a role in the tumor microenvironment in various types of cancer including colon cancer, hepatocellular carcinoma, and cutaneous T cell lymphoma.70