It is noted that expression of Q236A 14-3-3ε decreased CVB3 viral RNA levels concomitant with an increase in IFNB mRNA levels in CVB3-infected cells (MOI 5) (Fig. 6C and D), yet expression of Q236A 14-3-3ε did not decrease viral yield after multiple infection cycles (MOI 0.01, 24 hours) (Fig. 6D and G). This evidence concerns the gene IFNB1 and infection.