The biological events, triggered by the microglia and neurons upon irradiation with dual lasers (1,064- and 808-nm lasers, respectively), were studied extensively to realize the potential of this PBM method in reducing the fAβ burden and neurotoxicity in the AD model (D'Andrea et al., 2004; Bolmont et al., 2008; Cherry et al., 2014). This evidence concerns the gene FANCB and Alzheimer disease.