When hemopexin was administered continuously for 2 weeks directly into the ventricles of mice with Alzheimer’s disease that were 6 to 7 weeks old, and therefore were too young to develop dementia, memory impairment developed.28 Lipocalin 2, which is a factor associated with neuroinflammation in the murine brain, also increased. The gene discussed is HPX; the disease is memory impairment.