Through modulating different copies of both Ci−3P and GMR Gal4 to increase the amount of Ci−3P, we found that expression of one and two copies of Ci−3P with one (Figures 3A and 3C) or two copies of GMR Gal4 (Figures 3B and 3D), none of them could cause tumor-like eye phenotype. This evidence concerns the gene LGALS4 and neoplasm.