The findings presented in the previous sections as well as existing literature highlight the inextricable link between intestinal microbiotaand CRC epigenetic changes, irrespective of the role played by B. fragilis-associated miR-149-3p, pks+ E. coli-associated miR-20a-5p, or lncRNA ENO1-IT1. This evidence concerns the gene HAUS3 and colorectal carcinoma.