Zhang et al. (2017) demonstrated that the downregulation of miR-4505 by XLOC_000090 enhances the migration and invasion of lung cancer cells. Furthermore, Lcn2-mediated miR-4505 inhibited oral cancer metastasis and migration by targeting carbonic anhydrase IX (Lin et al., 2016). This evidence concerns the gene LCN2 and lip and oral cavity carcinoma.